Non-absorbed Antibiotics for IBS
نویسنده
چکیده
Public reporting burden for the collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the collection of information. Send comments regarding this burden estimate or any other aspect of this collection of information, including suggestions for reducing this burden, to Washington Headquarters Services, Directorate for Information Operations and Reports, 1215 Jefferson Davis Highway, Suite 1204, Arlington VA 22202-4302. Respondents should be aware that notwithstanding any other provision of law, no person shall be subject to a penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number.
منابع مشابه
The place of antibiotics in management of irritable bowel syndrome: a systematic review and meta-analysis
INTRODUCTION Irritable bowel syndrome (IBS) is a prevalent gastrointestinal disease with an obscure pathophysiology. Current treatments for IBS have modest efficacy at best and the need for a robust therapy for IBS remains unmet. As small intestinal bacterial overgrowth has been proposed to be involved in pathogenesis of IBS, antibacterial agents might be efficacious in treatment of this condit...
متن کاملBacteria and the Role of Antibiotics in Irritable Bowel Syndrome
INTRODUCTION Irritable bowel syndrome (IBS) is a functional gastrointestinal (GI) disorder characterized by symptoms, such as abdominal pain, bloating, diarrhea, and constipation, that are not attributable to structural or biochemical abnormalities (1). Although several conceptual models of IBS pathogenesis have been suggested, including visceral hypersensitivity, abnormal intestinal motility, ...
متن کاملAntibiotics as deep modulators of gut microbiota: between good and evil.
The recent increase in our knowledge of human gut microbiota has changed our view on antibiotics. Antibiotics are, indeed, no longer considered only beneficial, but also potentially harmful drugs, as their abuse appears to play a role in the pathogenesis of several disorders associated with microbiota impairment (eg, Clostridium difficile infection or metabolic disorders). Both drug-related fac...
متن کاملUse of broad-spectrum antibiotics and the development of irritable bowel syndrome.
BACKGROUND Irritable bowel syndrome (IBS) is a functional bowel disorder with an estimated prevalence of 9% to 22% in the United States. It is responsible for 28% of gastroenterology visits, with associated health care costs of $8 billion annually. Yet, IBS etiology is the subject of much debate. OBJECTIVES Our study examines a possible relationship between IBS and exposure to broad-spectrum ...
متن کاملRifaximin therapy for patients with irritable bowel syndrome without constipation.
BACKGROUND Evidence suggests that gut flora may play an important role in the pathophysiology of the irritable bowel syndrome (IBS). We evaluated rifaximin, a minimally absorbed antibiotic, as treatment for IBS. METHODS In two identically designed, phase 3, double-blind, placebo-controlled trials (TARGET 1 and TARGET 2), patients who had IBS without constipation were randomly assigned to eith...
متن کامل